Darifenacin Hydrobromide Darifenacin HBr CAS 133099-07-7 Assay ≥99.0% API Factory High Quality

Short Description:

Chemical Name: Darifenacin Hydrobromide

Synonyms: Darifenacin HBr; UK-88525

CAS: 133099-07-7

Appearance: White Crystalline Powder

Assay: ≥99.0%

Darifenacin HBr in the treatment of Overactive Bladder

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


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Description:

Manufacturer Supply with High Purity and Stable Quality
Chemical Name: Darifenacin Hydrobromide
CAS: 133099-07-7
Darifenacin hydrobromide is a selective M3 muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.
API High Quality, Commercial Production

Chemical Properties:

Chemical Name Darifenacin Hydrobromide 
Synonyms Darifenacin HBr; UK-88525; Enablex
CAS Number 133099-07-7
CAT Number RF-API94
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C28H30N2O2.HBr
Molecular Weight 507.46
Melting Point 228.0~230.0℃
Solubility DMSO: Soluble 20mg/ml, Clear
Storage Temperature Store Long-term at -20℃
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Crystalline Powder
Solubility  Sparingly Soluble in Methanol, Slightly Soluble in Water and Practically Insoluble in Chloroform
Identification IR Spectrum of the sample corresponds to that of reference standard
Identification HPLC The retention time of the major peak of the sample solution corresponds to that of the standard solution
Related Substances
Max. Single Impurity ≤0.50%
Total Impurities ≤1.0%
Optical Isomer ≤0.50%
Residual Solvents
Ethyl Acetate ≤0.50%
Ethanol ≤0.50%
Methanol ≤0.30%
Acetone ≤0.50%
1-Butanol ≤0.50%
Loss on Drying ≤1.0% (Dry at 105℃ in an electric air blowing dryer till a constant weight)
Residue on Ignition ≤0.10%
Heavy Metals ≤20ppm
Assay ≥99.0% (on dried basis)
Shelf Life 24 Months
Test Standard Enterprise Standard
Usage API, Overactive Bladder 

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

1

FAQ:

Application:

Darifenacin Hydrobromide, Darifenacin HBr (CAS 133099-07-7), an orally active, once a day selective M3 receptor antagonist, was launched for the treatment of overactive bladder in patients with symptoms of urge urinary incontinence, urgency and frequency. The drug selectively inhibits M3 receptor in the detrusor muscle while sparing the M1 and M2 receptors that are believed to be involved in central nervous system and cardiovascular function respectively. The compound was originally developed by Pfizer and licensed to Novartis and Bayer.  

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